2ZJD

Crystal Structure of LC3-p62 complex

Summary for 2ZJD

Entry DOI	10.2210/pdb2zjd/pdb
Descriptor	Microtubule-associated proteins 1A/1B light chain 3B precursor, undecameric peptide from Sequestosome-1 (3 entities in total)
Functional Keywords	p62, autophagy, lc3, microtubule-associated protein 1 light chain 3, cytoplasm, cytoplasmic vesicle, lipoprotein, membrane, ubl conjugation pathway, alternative splicing, apoptosis, differentiation, endosome, immune response, metal-binding, nucleus, phosphoprotein, zinc, zinc-finger, apoptosis inhibitor-apoptosis complex, apoptosis inhibitor/apoptosis
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm, cytoskeleton: Q9GZQ8 Cytoplasm: Q64337
Total number of polymer chains	4
Total formula weight	32623.28
Authors	Ichimura, Y.,Kumanomidou, T.,Sou, Y.,Mizushima, T.,Ezaki, J.,Ueno, T.,Kominami, E.,Yamane, T.,Tanaka, K.,Komatsu, M. (deposition date: 2008-03-05, release date: 2008-06-03, Last modification date: 2023-11-01)
Primary citation	Ichimura, Y.,Kumanomidou, T.,Sou, Y.-S.,Mizushima, T.,Ezaki, J.,Ueno, T.,Kominami, E.,Yamane, T.,Tanaka, K.,Komatsu, M. Structural Basis for Sorting Mechanism of p62 in Selective Autophagy J.Biol.Chem., 283:22847-22857, 2008 Cited by PubMed: 18524774 DOI: 10.1074/jbc.M802182200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.56 Å)

Structure validation