2ZIQ

Thrombin Inhibition

Summary for 2ZIQ

• Entry DOI: 10.2210/pdb2ziq/pdb
• Related: 2ZC9 2ZDA 2ZFP 2ZGB 2ZGX 2ZI2
• Related PRD ID: PRD_000596
• Descriptor: Thrombin light chain, Thrombin heavy chain, Hirudin variant-1, ... (7 entities in total)
• Functional Keywords: blood clotting, hydrolase inhibitor, acute phase, blood coagulation, cleavage on pair of basic residues, disease mutation, gamma-carboxyglutamic acid, glycoprotein, kringle, protease, secreted, serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted, extracellular space: P00734 P00734; Secreted: P01050
• Total number of polymer chains: 3
• Total formula weight: 35807.79

Authors

Baum, B.,Heine, A.,Klebe, G. (deposition date: 2008-02-20, release date: 2009-01-13, Last modification date: 2023-11-15)

• Primary citation: Baum, B.,Hangauer, D.,Heine, A.,Klebe, G.; Understanding Thrombin Inhibition; To be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)