2ZIN

Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with BocLys and an ATP analogue

Summary for 2ZIN

Entry DOI	10.2210/pdb2zin/pdb
Related	2E3C 2ZCD 2ZCE
Descriptor	Pyrrolysyl-tRNA synthetase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (6 entities in total)
Functional Keywords	aminoacyl-trna synthetase, pyrrolysyl-trna synthetase, pyrrolysine, trna, atp analogue, non-natural amino acid, unnatural amino acid, atp-binding, cytoplasm, ligase, nucleotide-binding, protein biosynthesis, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi
Biological source	Methanosarcina mazei
Cellular location	Cytoplasm (By similarity): Q8PWY1
Total number of polymer chains	1
Total formula weight	34207.34
Authors	Yanagisawa, T.,Ishii, R.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2008-02-19, release date: 2008-12-02, Last modification date: 2023-11-01)
Primary citation	Yanagisawa, T.,Ishii, R.,Fukunaga, R.,Kobayashi, T.,Sakamoto, K.,Yokoyama, S. Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode N(varepsilon)-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification Chem.Biol., 15:1187-1197, 2008 Cited by PubMed: 19022179 DOI: 10.1016/j.chembiol.2008.10.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.79 Å)

Structure validation