2ZFX

Crystal structure of the rat vitamin D receptor ligand binding domain complexed with YR301 and a synthetic peptide containing the NR2 box of DRIP 205

Summary for 2ZFX

Entry DOI	10.2210/pdb2zfx/pdb
Descriptor	Vitamin D3 receptor, DRIP 205 NR2 box peptide, (2S)-3-{4-[1-ethyl-1-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)propyl]-2-methylphenoxy}propane-1,2-diol, ... (4 entities in total)
Functional Keywords	hormone/growth factor receptor, dna-binding, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, zinc, zinc-finger, activator, alternative splicing, polymorphism
Biological source	Rattus norvegicus (rat) More
Cellular location	Nucleus: P13053 Q15648
Total number of polymer chains	2
Total formula weight	32085.03
Authors	Kakuda, S.,Takimoto-Kamimura, M. (deposition date: 2008-01-15, release date: 2009-01-20, Last modification date: 2024-03-13)
Primary citation	Kakuda, S.,Okada, K.,Eguchi, H.,Takenouchi, K.,Hakamata, W.,Kurihara, M.,Takimoto-Kamimura, M. Structure of the ligand-binding domain of rat VDR in complex with the nonsecosteroidal vitamin D3 analogue YR301 Acta Crystallogr.,Sect.F, 64:970-973, 2008 Cited by PubMed: 18997319 DOI: 10.1107/S1744309108026754 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation