2ZDY

Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4

Summary for 2ZDY

• Entry DOI: 10.2210/pdb2zdy/pdb
• Related: 2ZDX
• Descriptor: Pyruvate dehydrogenase kinase isozyme 4, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: pdk4, kinase, atp-binding, adp, carbohydrate metabolism, glucose metabolism, mitochondrion, phosphoprotein, transferase, transit peptide
• Biological source: Homo sapiens (Human)
• Cellular location: Mitochondrion matrix: Q16654
• Total number of polymer chains: 2
• Total formula weight: 90683.31

Authors

Kawamoto, M.,Shiromizu, I.,Kukimoto-Niino, M.,Tokmakov, A.,Terada, T.,Shirouzu, M.,Matsusue, T.,Yokoyama, S. (deposition date: 2007-12-01, release date: 2008-12-09, Last modification date: 2023-11-01)

• Primary citation: Kukimoto-Niino, M.,Tokmakov, A.,Terada, T.,Ohbayashi, N.,Fujimoto, T.,Gomi, S.,Shiromizu, I.,Kawamoto, M.,Matsusue, T.,Shirouzu, M.,Yokoyama, S.; Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4.; Acta Crystallogr.,Sect.D, 67:763-773, 2011; PubMed: 21904029; DOI: 10.1107/S090744491102405X

Experimental method

X-RAY DIFFRACTION (2.4 Å)