2Z7X

Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

2Z7X の概要

• エントリーDOI: 10.2210/pdb2z7x/pdb
• 関連するPDBエントリー: 2Z80 2Z81 2Z82
• 分子名称: Toll-like receptor 2,Variable lymphocyte receptor B, (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, Toll-like receptor 1,Variable lymphocyte receptor B, ... (11 entities in total)
• 機能のキーワード: tlr2, tlr1, pam3csk4, lipopeptide, innate immunity, glycoprotein, immune response, inflammatory response, leucine-rich repeat, membrane, receptor, transmembrane, cytoplasmic vesicle, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 126181.40

構造登録者

Lee, J.O.,Jin, M.S.,Kim, S.E.,Heo, J.Y. (登録日: 2007-08-29, 公開日: 2007-10-02, 最終更新日: 2024-02-07)

• 主引用文献: Jin, M.S.,Kim, S.E.,Heo, J.Y.,Lee, M.E.,Kim, H.M.,Paik, S.G.,Lee, H.,Lee, J.O.; Crystal Structure of the TLR1-TLR2 Heterodimer Induced by Binding of a Tri-Acylated Lipopeptide; Cell(Cambridge,Mass.), 130:1071-1082, 2007; PubMed: 17889651; DOI: 10.1016/j.cell.2007.09.008

実験手法

X-RAY DIFFRACTION (2.1 Å)