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2YY2

Crystal structure of the human Phosphodiesterase 9A catalytic domain complexed with IBMX

Summary for 2YY2
Entry DOI10.2210/pdb2yy2/pdb
DescriptorHigh-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, ZINC ION, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordscatalytic domain, phosphodiesterase, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationIsoform PDE9A1: Cell projection, ruffle membrane. Isoform PDE9A2: Cell projection, ruffle membrane. Isoform PDE9A3: Cytoplasm. Isoform PDE9A17: Cytoplasm: O76083
Total number of polymer chains2
Total formula weight78755.98
Authors
Handa, N.,Shirouzu, M.,Terada, T.,Omori, K.,Kotera, J.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2007-04-27, release date: 2007-10-30, Last modification date: 2023-10-25)
Primary citationHanda, N.,Shirouzu, M.,Terada, T.,Omori, K.,Kotera, J.,Yokoyama, S.
Crystal structure of the human Phosphodiesterase 9A catalytic domain
To be Published,
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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