2YQ7

Structure of Bcl-xL bound to BimLOCK

Summary for 2YQ7

• Entry DOI: 10.2210/pdb2yq7/pdb
• Related: 2YQ6
• Descriptor: BCL-2-LIKE PROTEIN 1, BCL-2-LIKE PROTEIN 11, GLYCEROL, ... (4 entities in total)
• Functional Keywords: constrained peptide, apoptosis, bcl-2 family
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 20223.52

Authors

Smith, B.J.,Czabotar, P.E. (deposition date: 2012-11-06, release date: 2012-11-28, Last modification date: 2023-12-20)

• Primary citation: Okamoto, T.,Zobel, K.,Fedorova, A.,Quan, C.,Yang, H.,Fairbrother, W.J.,Huang, D.C.S.,Smith, B.J.,Deshayes, K.,Czabotar, P.E.; Stabilizing the Pro-Apoptotic Bimbh3 Helix (Bimsahb) Does not Necessarily Enhance Affinity or Biological Activity.; Acs Chem.Biol., 8:297-, 2013; PubMed: 23151250; DOI: 10.1021/CB3005403

Experimental method

X-RAY DIFFRACTION (1.901 Å)