2YME

Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with granisetron

Summary for 2YME

Entry DOI	10.2210/pdb2yme/pdb
Related	2YMD
Descriptor	SOLUBLE ACETYLCHOLINE RECEPTOR, 2-acetamido-2-deoxy-beta-D-glucopyranose, 1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide, ... (6 entities in total)
Functional Keywords	receptor, pentameric ligand-gated ion channel
Biological source	APLYSIA CALIFORNICA (CALIFORNIA SEA HARE)
Total number of polymer chains	10
Total formula weight	239044.18
Authors	Kesters, D.,Thompson, A.J.,Brams, M.,Elk, R.v.,Spurny, R.,Geitmann, M.,Villalgordo, J.M.,Guskov, A.,Danielson, U.H.,Lummis, S.C.R.,Smit, A.B.,Ulens, C. (deposition date: 2012-10-09, release date: 2012-12-26, Last modification date: 2023-12-20)
Primary citation	Kesters, D.,Thompson, A.J.,Brams, M.,Van Elk, R.,Spurny, R.,Geitmann, M.,Villalgordo, J.M.,Guskov, A.,Helena Danielson, U.,Lummis, S.C.R.,Smit, A.B.,Ulens, C. Structural Basis of Ligand Recognition in 5-Ht3 Receptors. Embo Rep., 14:49-, 2013 Cited by PubMed: 23196367 DOI: 10.1038/EMBOR.2012.189 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation