2YLA

INHIBITION OF THE PNEUMOCOCCAL VIRULENCE FACTOR STRH AND MOLECULAR INSIGHTS INTO N-GLYCAN RECOGNITION AND HYDROLYSIS

Summary for 2YLA

• Entry DOI: 10.2210/pdb2yla/pdb
• Related: 2YL5 2YL6 2YL8 2YL9 2YLL
• Descriptor: BETA-N-ACETYLHEXOSAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: hydrolase
• Biological source: STREPTOCOCCUS PNEUMONIAE
• Cellular location: Secreted, cell wall; Peptidoglycan-anchor (Potential): P49610
• Total number of polymer chains: 4
• Total formula weight: 203066.34

Authors

Pluvinage, B.,Higgins, M.A.,Abbott, D.W.,Robb, C.,Dalia, A.B.,Deng, L.,Weiser, J.N.,Parsons, T.B.,Fairbanks, A.J.,Vocadlo, D.J.,Boraston, A.B. (deposition date: 2011-06-01, release date: 2011-09-07, Last modification date: 2020-07-29)

• Primary citation: Pluvinage, B.,Higgins, M.A.,Abbott, D.W.,Robb, C.,Dalia, A.B.,Deng, L.,Weiser, J.N.,Parsons, T.B.,Fairbanks, A.J.,Vocadlo, D.J.,Boraston, A.B.; Inhibition of the Pneumococcal Virulence Factor Strh and Molecular Insights Into N-Glycan Recognition and Hydrolysis.; Structure, 19:1603-, 2011; PubMed: 22078560; DOI: 10.1016/J.STR.2011.08.011

Experimental method

X-RAY DIFFRACTION (2.7 Å)