2YID

Crystal structure of the SucA domain of Mycobacterium smegmatis alpha- ketoglutarate decarboxylase in complex with the enamine-ThDP intermediate

Summary for 2YID

Entry DOI	10.2210/pdb2yid/pdb
Related	2XT6 2XT8 2XT9 2XTA 2Y0P 2YIC
Descriptor	2-OXOGLUTARATE DECARBOXYLASE, (4E)-4-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-4-methyl-1,3-thiazol-2(3H)-ylidene}-4-hydroxybutanoic acid, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	lyase, thdp-covalent adduct
Biological source	MYCOBACTERIUM SMEGMATIS
Total number of polymer chains	4
Total formula weight	391029.70
Authors	Wagner, T.,Bellinzoni, M.,Wehenkel, A.M.,O'Hare, H.M.,Alzari, P.M. (deposition date: 2011-05-11, release date: 2011-06-15, Last modification date: 2023-12-20)
Primary citation	Wagner, T.,Bellinzoni, M.,Wehenkel, A.M.,O'Hare, H.M.,Alzari, P.M. Functional Plasticity and Allosteric Regulation of Alpha-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism. Chem.Biol., 18:1011-, 2011 Cited by PubMed: 21867916 DOI: 10.1016/J.CHEMBIOL.2011.06.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation