2YAY

The Crystal Structure of Leishmania major dUTPase in complex with substrate analogue dUpNpp

Summary for 2YAY

• Entry DOI: 10.2210/pdb2yay/pdb
• Related: 2CIC 2CJE 2YAZ 2YB0
• Descriptor: DUTPASE, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: hydrolase, leishmaniasis
• Biological source: LEISHMANIA MAJOR
• Total number of polymer chains: 1
• Total formula weight: 31157.16

Authors

Hemsworth, G.R.,Moroz, O.V.,Fogg, M.J.,Scott, B.,Bosch-Navarrete, C.,Gonzalez-Pacanowska, D.,Wilson, K.S. (deposition date: 2011-02-25, release date: 2011-03-16, Last modification date: 2023-12-20)

• Primary citation: Hemsworth, G.R.,Moroz, O.V.,Fogg, M.J.,Scott, B.,Bosch-Navarrete, C.,Gonzalez-Pacanowska, D.,Wilson, K.S.; The Crystal Structure of the Leishmania Major Deoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, Dump, and Deoxyuridine.; J.Biol.Chem., 286:16470-, 2011; PubMed: 21454646; DOI: 10.1074/JBC.M111.224873

Experimental method

X-RAY DIFFRACTION (1.86 Å)