2YAT

Crystal structure of estradiol derived metal chelate and estrogen receptor-ligand binding domain complex

Summary for 2YAT

Entry DOI	10.2210/pdb2yat/pdb
Related	1A52 1AKF 1ERE 1ERR 1G50 1GWQ 1GWR 1HCP 1HCQ 1L2I 1PCG 1QKT 1QKU 1R5K 1SJ0 1UOM 1X7E 1X7R 1XP1 1XP6 1XP9 1XPC 1XQC 1YIM 1YIN 1ZKY 2AYR 2B1V 2BJ4 2FAI 2JF9 2JFA 3ERD 3ERT
Descriptor	ESTROGEN RECEPTOR, EUROPIUM ION, ESTRADIOL-PYRIDINIUM TETRAACETIC ACID, ... (5 entities in total)
Functional Keywords	transcription
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Isoform 1: Nucleus. Isoform 3: Nucleus: P03372
Total number of polymer chains	1
Total formula weight	29681.53
Authors	Li, M.J.,Greenblatt, H.M.,Dym, O.,Albeck, S.,Degani, H.,Sussman, J.L. (deposition date: 2011-02-24, release date: 2011-06-01, Last modification date: 2023-12-20)
Primary citation	Li, M.J.,Greenblatt, H.M.,Dym, O.,Albeck, S.,Pais, A.,Gunanathan, C.,Milstein, D.,Degani, H.,Sussman, J.L. Structure of Estradiol Metal Chelate and Estrogen Receptor Complex: The Basis for Designing a New Class of Selective Estrogen Receptor Modulators. J.Med.Chem., 54:3575-, 2011 Cited by PubMed: 21473635 DOI: 10.1021/JM200192Y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.602 Å)

Structure validation