2Y1Z

Human alphaB Crystallin ACD R120G

Summary for 2Y1Z

• Entry DOI: 10.2210/pdb2y1z/pdb
• Related: 2WJ7 2Y1Y 2Y22
• Descriptor: ALPHA-CRYSTALLIN B CHAIN, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• Functional Keywords: small heat shock protein, chaperone, stress protein, eye lens protein, cataract
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm: P02511
• Total number of polymer chains: 2
• Total formula weight: 21766.69

Authors

Clark, A.R.,Bagneris, C.,Naylor, C.E.,Keep, N.H.,Slingsby, C. (deposition date: 2010-12-10, release date: 2011-03-02, Last modification date: 2011-07-13)

• Primary citation: Clark, A.R.,Naylor, C.E.,Bagneris, C.,Keep, N.H.,Slingsby, C.; Crystal Structure of R120G Disease Mutant of Human Alphab-Crystallin Domain Dimer Shows Closure of a Groove; J.Mol.Biol., 408:118-, 2011; PubMed: 21329698; DOI: 10.1016/J.JMB.2011.02.020

Experimental method

X-RAY DIFFRACTION (2.5 Å)