2Y1K

STRUCTURE OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY CBDP (12H SOAK): PHOSPHOSERINE ADDUCT

Summary for 2Y1K

Entry DOI	10.2210/pdb2y1k/pdb
Related	1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW 2J4C 2WID 2WIF 2WIG 2WIJ 2WIK 2WIL 2WSL 2XMB 2XMC 2XMD 2XMG 2XQF 2XQG 2XQI 2XQJ 2XQK
Descriptor	CHOLINESTERASE, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (9 entities in total)
Functional Keywords	hydrolase, inhibition, aging
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	62654.43
Authors	Carletti, E.,Colletier, J.P.,Nachon, F.,Weik, M. (deposition date: 2010-12-08, release date: 2011-06-29, Last modification date: 2023-12-20)
Primary citation	Carletti, E.,Schopfer, L.M.,Colletier, J.P.,Froment, M.T.,Nachon, F.,Weik, M.,Lockridge, O.,Masson, P. Reaction of Cresyl Saligenin Phosphate, the Organophosphorus Agent Implicated in Aerotoxic Syndrome, with Human Cholinesterases: Mechanistic Studies Employing Kinetics, Mass Spectrometry, and X-Ray Structure Analysis. Chem.Res.Toxicol., 24:797-, 2011 Cited by PubMed: 21438623 DOI: 10.1021/TX100447K PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation