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2XWE

X-RAY STRUCTURE OF ACID-BETA-GLUCOSIDASE WITH 5N,6S-(N'-(N-OCTYL)IMINO)-6-THIONOJIRIMYCIN IN THE ACTIVE SITE

Summary for 2XWE
Entry DOI10.2210/pdb2xwe/pdb
Related1OGS 1Y7V 2F61 2J25 2V3D 2V3E 2V3F 2WCG 2WKL 2XWD
DescriptorGLUCOSYLCERAMIDASE, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... (6 entities in total)
Functional Keywordsglucocerebrosidase, hydrolase, gaucher disease, sphingolipid metabolism
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total formula weight115576.99
Authors
Brumshtein, B.,Aguilar-Moncayo, M.,Benito, J.M.,Ortiz Mellet, C.,Garcia Fernandez, J.M.,Silman, I.,Shaaltiel, Y.,Sussman, J.L.,Futerman, A.H. (deposition date: 2010-11-02, release date: 2011-09-14, Last modification date: 2023-12-20)
Primary citationBrumshtein, B.,Aguilar-Moncayo, M.,Benito, J.M.,Garcia Fernandez, J.M.,Silman, I.,Shaaltiel, Y.,Aviezer, D.,Sussman, J.L.,Futerman, A.H.,Ortiz Mellet, C.
Cyclodextrin-Mediated Crystallization of Acid Beta-Glucosidase in Complex with Amphiphilic Bicyclic Nojirimycin Analogues.
Org.Biomol.Chem., 9:4160-, 2011
Cited by
PubMed: 21483943
DOI: 10.1039/C1OB05200D
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.31 Å)
Structure validation

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