2XU0

Crystal structure of the NTS-DBL1(alpha-1) domain of the Plasmodium falciparum membrane protein 1 (PfEMP1) from the varO strain.

Summary for 2XU0

Entry DOI	10.2210/pdb2xu0/pdb
Descriptor	ERYTHROCYTE MEMBRANE PROTEIN 1, PROLINE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	membrane protein, adhesion, virulence, duffy-binding-like-domain
Biological source	PLASMODIUM FALCIPARUM PALO ALTO/UGANDA
Total number of polymer chains	1
Total formula weight	56921.83
Authors	Juillerat, A.,Lewit-Bentley, A.,Guillotte, M.,Vigan-Womas, I.,Hessler, A.,Gangnard, S.,England, P.,Mercereau-Puijalon, O.,Bentley, G.A. (deposition date: 2010-10-14, release date: 2011-04-06, Last modification date: 2019-03-06)
Primary citation	Juillerat, A.,Lewit-Bentley, A.,Guillotte, M.,Gangnard, S.,Hessel, A.,Baron, B.,Vigan-Womas, I.,England, P.,Mercereau-Puijalon, O.,Bentley, G.A. Structure of a Plasmodium Falciparum Pfemp1 Rosetting Domain Reveals a Role for the N-Terminal Segment in Heparin-Mediated Rosette Inhibition. Proc.Natl.Acad.Sci.USA, 108:5243-, 2011 Cited by PubMed: 21402930 DOI: 10.1073/PNAS.1018692108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.06 Å)

Structure validation