2XS6

CRYSTAL STRUCTURE OF THE RHOGAP DOMAIN OF HUMAN PIK3R2

Summary for 2XS6

Entry DOI	10.2210/pdb2xs6/pdb
Descriptor	PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA, CHLORIDE ION (3 entities in total)
Functional Keywords	structural genomics consortium, sgc, transferase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	22988.50
Authors	Tresaugues, L.,Welin, M.,Arrowsmith, C.H.,Berglund, H.,Bountra, C.,Collins, R.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Johansson, I.,Karlberg, T.,Kol, S.,Kotenyova, T.,Kouznetsova, E.,Moche, M.,Nyman, T.,Persson, C.,Schuler, H.,Schutz, P.,Siponen, M.I.,Thorsell, A.G.,van der Berg, S.,Wahlberg, E.,Weigelt, J.,Nordlund, P. (deposition date: 2010-09-24, release date: 2010-11-17, Last modification date: 2023-12-20)
Primary citation	Lim, S.M.,Yeung, K.,Tresaugues, L.,Ling, T.H.,Nordlund, P. The Structure and Catalytic Mechanism of Human Sphingomyelin Phosphodiesterase Like 3A - an Acid Sphingomyelinase Homolog with a Novel Nucleotide Hydrolase Activity. FEBS J., 283:1107-, 2016 Cited by PubMed: 26783088 DOI: 10.1111/FEBS.13655 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.09 Å)

Structure validation