2XRC
Human complement factor I
Summary for 2XRC
| Entry DOI | 10.2210/pdb2xrc/pdb |
| Descriptor | HUMAN COMPLEMENT FACTOR I, CALCIUM ION, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
| Functional Keywords | immune system, hydrolase, conglutinogen activating factor, serine protease, complement system |
| Biological source | HOMO SAPIENS (HUMAN) |
| Cellular location | Secreted, extracellular space: P05156 |
| Total number of polymer chains | 4 |
| Total formula weight | 259336.62 |
| Authors | Roversi, P.,Johnson, S.,Lea, S.M. (deposition date: 2010-09-13, release date: 2011-07-13, Last modification date: 2023-12-20) |
| Primary citation | Roversi, P.,Johnson, S.,Caesar, J.J.,Mclean, F.,Leath, K.J.,Tsiftsoglou, S.A.,Morgan, B.P.,Harris, C.L.,Sim, R.B.,Lea, S.M. Structural Basis for Complement Factor I Control and its Disease-Associated Sequence Polymorphisms. Proc.Natl.Acad.Sci.USA, 108:12839-, 2011 Cited by PubMed: 21768352DOI: 10.1073/PNAS.1102167108 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.69 Å) |
Structure validation
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