2XQF

X-ray Structure of human butyrylcholinesterase inhibited by racemic VX

Summary for 2XQF

Entry DOI	10.2210/pdb2xqf/pdb
Related	1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW 2J4C 2WID 2WIF 2WIG 2WIJ 2WIK 2WIL 2WSL 2XMB 2XMC 2XMD 2XMG 2XQG 2XQI 2XQJ 2XQK
Descriptor	CHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
Functional Keywords	hydrolase, nerve agent, bioscavenger
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	62019.49
Authors	Wandhammer, M.,Carletti, E.,Gillon, E.,Masson, P.,Goeldner, M.,Noort, D.,Nachon, F. (deposition date: 2010-09-02, release date: 2011-03-23, Last modification date: 2023-12-20)
Primary citation	Wandhammer, M.,Carletti, E.,Van Der Schans, M.,Gillon, E.,Nicolet, Y.,Masson, P.,Goeldner, M.,Noort, D.,Nachon, F. Structural Study of the Complex Stereoselectivity of Human Butyrylcholinesterase for the Neurotoxic V-Agents. J.Biol.Chem., 286:16783-, 2011 Cited by PubMed: 21454498 DOI: 10.1074/JBC.M110.209569 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation