2XN4

Crystal structure of the kelch domain of human KLHL2 (Mayven)

Summary for 2XN4

Entry DOI	10.2210/pdb2xn4/pdb
Descriptor	KELCH-LIKE PROTEIN 2, SODIUM ION, SULFATE ION, ... (5 entities in total)
Functional Keywords	structural protein, cytoskeleton
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm, cytoskeleton: O95198
Total number of polymer chains	2
Total formula weight	66407.02
Authors	Canning, P.,Hozjan, V.,Cooper, C.D.O.,Ayinampudi, V.,Vollmar, M.,Pike, A.C.W.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N. (deposition date: 2010-07-30, release date: 2010-08-18, Last modification date: 2023-12-20)
Primary citation	Canning, P.,Cooper, C.D.O.,Krojer, T.,Murray, J.W.,Pike, A.C.W.,Chaikuad, A.,Keates, T.,Thangaratnarajah, C.,Hojzan, V.,Marsden, B.D.,Gileadi, O.,Knapp, S.,von Delft, F.,Bullock, A.N. Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases. J.Biol.Chem., 288:7803-, 2013 Cited by PubMed: 23349464 DOI: 10.1074/JBC.M112.437996 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation