2XA5

Structure of substrate binding protein SiaP (A11N) in complex with Neu5Ac

Summary for 2XA5

Entry DOI	10.2210/pdb2xa5/pdb
Related	2CEX 2CEY 2V4C 2WX9 2WYK 2WYP 3B50
Descriptor	SIALIC ACID-BINDING PERIPLASMIC PROTEIN SIAP, N-acetyl-beta-neuraminic acid (3 entities in total)
Functional Keywords	sugar binding protein, neu5ac, sbp, esr, periplasmic binding protein, trap, transport protein
Biological source	HAEMOPHILUS INFLUENZAE
Total number of polymer chains	1
Total formula weight	35384.91
Authors	Fischer, M.,Hubbard, R.E. (deposition date: 2010-03-26, release date: 2011-04-06, Last modification date: 2023-12-20)
Primary citation	Darby, J.F.,Hopkins, A.P.,Shimizu, S.,Roberts, S.M.,Brannigan, J.A.,Turkenburg, J.P.,Thomas, G.H.,Hubbard, R.E.,Fischer, M. Water networks can determine the affinity of ligand binding to proteins. J.Am.Chem.Soc., 2019 Cited by PubMed: 31518131 DOI: 10.1021/jacs.9b06275 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.09 Å)

Structure validation