2X72

CRYSTAL STRUCTURE OF THE CONSTITUTIVELY ACTIVE E113Q,D2C,D282C RHODOPSIN MUTANT WITH BOUND GALPHACT PEPTIDE.

Summary for 2X72

• Entry DOI: 10.2210/pdb2x72/pdb
• Related: 1AQG 1BOJ 1BOK 1EDS 1EDV 1EDW 1EDX 1F88 1FDF 1FQJ 1FQK 1GZM 1HZX 1JFP 1L9H 1LN6 1LVZ 1N3M 1NZS 1OV0 1OV1 1TAD 1TAG 1TND 1U19 1VQX 2I35 2I36 2I37 2J4Y
• Descriptor: RHODOPSIN, GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
• Functional Keywords: signaling protein, chromophore, lipoprotein, glycoprotein, transmembrane, retinal protein, g-protein coupled receptor, sensory transduction, photoreceptor protein
• Biological source: BOS TAURUS (CATTLE); More
• Total number of polymer chains: 2
• Total formula weight: 43699.47

Authors

Standfuss, J.,Edwards, P.C.,Dantona, A.,Fransen, M.,Xie, G.,Oprian, D.D.,Schertler, G.F.X. (deposition date: 2010-02-22, release date: 2011-03-16, Last modification date: 2023-12-20)

• Primary citation: Standfuss, J.,Edwards, P.C.,Dantona, A.,Fransen, M.,Xie, G.,Oprian, D.D.,Schertler, G.F.X.; The Structural Basis of Agonist Induced Activation in Constitutively Active Rhodopsin; Nature, 471:656-, 2011; PubMed: 21389983; DOI: 10.1038/NATURE09795

Experimental method

X-RAY DIFFRACTION (3 Å)