2WQN

Structure of ADP-bound human Nek7

Summary for 2WQN

• Entry DOI: 10.2210/pdb2wqn/pdb
• Related: 2WQM 2WQO
• Descriptor: SERINE/THREONINE-PROTEIN KINASE NEK7, ADENOSINE-5'-DIPHOSPHATE, NICKEL (II) ION, ... (6 entities in total)
• Functional Keywords: atp-binding, polymorphism, metal-binding, serine/threonine-protein kinase, mitosis, cytoplasm, transferase, phosphoprotein, protein kinase, nucleotide-binding
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 36276.38

Authors

Richards, M.W.,Bayliss, R. (deposition date: 2009-08-24, release date: 2009-12-08, Last modification date: 2023-12-20)

• Primary citation: Richards, M.W.,O'Regan, L.,Mas-Droux, C.,Blot, J.M.,Cheung, J.,Hoelder, S.,Fry, A.M.,Bayliss, R.; An Autoinhibitory Tyrosine Motif in the Cell-Cycle- Regulated Nek7 Kinase is Released Through Binding of Nek9.; Mol.Cell, 36:560-, 2009; PubMed: 19941817; DOI: 10.1016/J.MOLCEL.2009.09.038

Experimental method

X-RAY DIFFRACTION (2.3 Å)