2WQE

Structure of S155R Aurora-A somatic mutant

Summary for 2WQE

• Entry DOI: 10.2210/pdb2wqe/pdb
• Related: 1MQ4 1MUO 1OL5 1OL6 1OL7 2BMC 2C6D 2C6E 2J4Z 2J50 2W1C 2W1D 2W1E 2W1F 2W1G
• Descriptor: SERINE/THREONINE-PROTEIN KINASE 6, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
• Functional Keywords: polymorphism, phosphoprotein, nucleotide-binding, cell cycle, transferase
• Biological source: HOMO SAPIENS
• Cellular location: Cytoplasm, cytoskeleton, centrosome: O14965
• Total number of polymer chains: 1
• Total formula weight: 31788.67

Authors

Bibby, R.,Bayliss, R. (deposition date: 2009-08-20, release date: 2009-09-29, Last modification date: 2023-12-20)

• Primary citation: Bibby, R.A.,Tang, C.,Faisal, A.,Drosopoulos, K.,Lubbe, S.,Houlston, R.,Bayliss, R.,Linardopoulos, S.; A Cancer Associated Aurora-A Mutant is Mislocalised and Misregulated due to Loss of Interaction with Tpx2.; J.Biol.Chem., 284:33177-, 2009; PubMed: 19801554; DOI: 10.1074/JBC.M109.032722

Experimental method

X-RAY DIFFRACTION (2.5 Å)