2WNU

Complex between c1q globular heads and heparan sulfate

Summary for 2WNU

• Entry DOI: 10.2210/pdb2wnu/pdb
• Related: 1PK6 2JG8 2JG9 2WNV
• Descriptor: COMPLEMENT C1Q SUBCOMPONENT SUBUNIT A, COMPLEMENT C1Q SUBCOMPONENT SUBUNIT B, COMPLEMENT C1Q SUBCOMPONENT SUBUNIT C, ... (6 entities in total)
• Functional Keywords: collagen, innate immunity, immune response, pyrrolidone carboxylic acid, immune system, disease mutation, complement pathway, glycoprotein, hydroxylation
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 6
• Total formula weight: 90704.41

Authors

Garlatti, V.,Chouquet, A.,Lunardi, T.,Thielens, N.M.,Arlaud, G.J.,Gaboriaud, C. (deposition date: 2009-07-20, release date: 2010-05-26, Last modification date: 2023-12-13)

• Primary citation: Garlatti, V.,Chouquet, A.,Lunardi, T.,Vives, R.,Paidassi, H.,Lortat-Jacob, H.,Thielens, N.M.,Arlaud, G.J.,Gaboriaud, C.; Cutting Edge: C1Q Binds Deoxyribose and Heparan Sulfate Through Neighboring Sites of its Recognition Domain.; J.Immunol., 185:808-, 2010; PubMed: 20548024; DOI: 10.4049/JIMMUNOL.1000184

Experimental method

X-RAY DIFFRACTION (2.3 Å)