2WIL

AGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA5

Summary for 2WIL

• Entry DOI: 10.2210/pdb2wil/pdb
• Related: 1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW 2J4C 2WID 2WIF 2WIG 2WIJ 2WIK
• Descriptor: CHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ethylphosphoramidic acid, ... (7 entities in total)
• Functional Keywords: aging, hydrolase, inhibition, polymorphism, glycoprotein, serine esterase, disease mutation
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 123554.10

Authors

Carletti, E.,Aurbek, N.,Gillon, E.,Loiodice, M.,Nicolet, Y.,Fontecilla, J.,Masson, P.,Thiermann, H.,Nachon, F.,Worek, F. (deposition date: 2009-05-12, release date: 2009-05-26, Last modification date: 2023-12-13)

• Primary citation: Carletti, E.,Aurbek, N.,Gillon, E.,Loiodice, M.,Nicolet, Y.,Fontecilla, J.,Masson, P.,Thiermann, H.,Nachon, F.,Worek, F.; Structure-Activity Analysis of Aging and Reactivation of Human Butyrylcholinesterase Inhibited by Analogues of Tabun; Biochem.J., 421:97-, 2009; PubMed: 19368529; DOI: 10.1042/BJ20090091

Experimental method

X-RAY DIFFRACTION (3.1 Å)