2WCD

Crystal structure of the assembled cytolysin A pore

Summary for 2WCD

• Entry DOI: 10.2210/pdb2wcd/pdb
• Related: 1QOY
• Descriptor: HEMOLYSIN E, CHROMOSOMAL, ETHYL MERCURY ION (2 entities in total)
• Functional Keywords: cytolytic protein, pore-forming toxin, transmembrane pore, toxin, membrane, secreted, cytolysis, periplasm, hemolysis, transmembrane, disulfide bond
• Biological source: ESCHERICHIA COLI
• Cellular location: Secreted: P77335
• Total number of polymer chains: 24
• Total formula weight: 842006.28

Authors

Mueller, M.,Grauschopf, U.,Maier, T.,Glockshuber, R.,Ban, N. (deposition date: 2009-03-11, release date: 2009-05-05, Last modification date: 2011-07-13)

• Primary citation: Mueller, M.,Grauschopf, U.,Maier, T.,Glockshuber, R.,Ban, N.; The Structure of a Cytolytic Alpha-Helical Toxin Pore Reveals its Assembly Mechanism; Nature, 459:726-, 2009; PubMed: 19421192; DOI: 10.1038/NATURE08026

Experimental method

X-RAY DIFFRACTION (3.29 Å)