2W0P

Crystal structure of the filamin A repeat 21 complexed with the migfilin peptide

Summary for 2W0P

Entry DOI	10.2210/pdb2w0p/pdb
Related	2AAV 2BP3 2BRQ 2J3S 2JF1
Descriptor	FILAMIN-A, FILAMIN-BINDING LIM PROTEIN 1, SULFATE ION, ... (4 entities in total)
Functional Keywords	alternative splicing, cytoskeleton-complex, phosphoprotein, disease mutation, immunoglobulin like, zinc, filamin, complex, integrin, migfilin, receptor, polymorphism, cytoskeleton, actin-binding, cell junction, cell adhesion, metal-binding, cytoplasm, lim domain, cell shape, acetylation
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Cytoplasm, cell cortex: P21333 Q8WUP2
Total number of polymer chains	3
Total formula weight	21220.36
Authors	Ruskamo, S.,Ylanne, J. (deposition date: 2008-08-20, release date: 2008-09-30, Last modification date: 2023-12-13)
Primary citation	Lad, Y.,Jiang, P.,Ruskamo, S.,Harburger, D.S.,Ylanne, J.,Campbell, I.D.,Calderwood, D.A. Structural Basis of the Migfilin-Filamin Interaction and Competition with Integrin {Beta} Tails. J.Biol.Chem., 283:35154-, 2008 Cited by PubMed: 18829455 DOI: 10.1074/JBC.M802592200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation