2VVN
BtGH84 in complex with NH-Butylthiazoline
Summary for 2VVN
Entry DOI | 10.2210/pdb2vvn/pdb |
Related | 2CHN 2CHO 2J47 2J4G 2JIW |
Descriptor | O-GLCNACASE BT_4395, GLYCEROL, AMMONIUM ION, ... (5 entities in total) |
Functional Keywords | glycoside hydrolase, complex, hydrolase, inhibitor, glycosidase |
Biological source | BACTEROIDES THETAIOTAOMICRON |
Total number of polymer chains | 2 |
Total formula weight | 169782.57 |
Authors | He, Y.,Davies, G.J. (deposition date: 2008-06-10, release date: 2008-07-01, Last modification date: 2023-12-13) |
Primary citation | Yuzwa, S.A.,Macauley, M.S.,Heinonen, J.E.,Shan, X.,Dennis, R.J.,He, Y.,Whitworth, G.E.,Stubbs, K.A.,Mceachern, E.J.,Davies, G.J.,Vocadlo, D.J. A Potent Mechanism-Inspired O-Glcnacase Inhibitor that Blocks Phosphorylation of Tau in Vivo. Nat.Chem.Biol., 4:483-, 2008 Cited by PubMed: 18587388DOI: 10.1038/NCHEMBIO.96 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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