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2VVN

BtGH84 in complex with NH-Butylthiazoline

Summary for 2VVN
Entry DOI10.2210/pdb2vvn/pdb
Related2CHN 2CHO 2J47 2J4G 2JIW
DescriptorO-GLCNACASE BT_4395, GLYCEROL, AMMONIUM ION, ... (5 entities in total)
Functional Keywordsglycoside hydrolase, complex, hydrolase, inhibitor, glycosidase
Biological sourceBACTEROIDES THETAIOTAOMICRON
Total number of polymer chains2
Total formula weight169782.57
Authors
He, Y.,Davies, G.J. (deposition date: 2008-06-10, release date: 2008-07-01, Last modification date: 2023-12-13)
Primary citationYuzwa, S.A.,Macauley, M.S.,Heinonen, J.E.,Shan, X.,Dennis, R.J.,He, Y.,Whitworth, G.E.,Stubbs, K.A.,Mceachern, E.J.,Davies, G.J.,Vocadlo, D.J.
A Potent Mechanism-Inspired O-Glcnacase Inhibitor that Blocks Phosphorylation of Tau in Vivo.
Nat.Chem.Biol., 4:483-, 2008
Cited by
PubMed: 18587388
DOI: 10.1038/NCHEMBIO.96
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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