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2VGI

HUMAN ERYTHROCYTE PYRUVATE KINASE: R486W MUTANT

Replaces:  1LIX
Summary for 2VGI
Entry DOI10.2210/pdb2vgi/pdb
Related2VGB 2VGF 2VGG
DescriptorPYRUVATE KINASE ISOZYMES R/L, 1,6-di-O-phosphono-beta-D-fructofuranose, 2-PHOSPHOGLYCOLIC ACID, ... (5 entities in total)
Functional Keywordsglycolysis, transferase
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains4
Total formula weight230374.09
Authors
Valentini, G.,Chiarelli, L.,Fortin, R.,Dolzan, M.,Galizzi, A.,Abraham, D.J.,Wang, C.,Bianchi, P.,Zanella, A.,Mattevi, A. (deposition date: 2007-11-13, release date: 2007-11-20, Last modification date: 2023-12-13)
Primary citationValentini, G.,Chiarelli, L.R.,Fortin, R.,Dolzan, M.,Galizzi, A.,Abraham, D.J.,Wang, C.,Bianchi, P.,Zanella, A.,Mattevi, A.
Structure and Function of Human Erythrocyte Pyruvate Kinase. Molecular Basis of Nonspherocytic Hemolytic Anemia.
J.Biol.Chem., 277:23807-, 2002
Cited by
PubMed: 11960989
DOI: 10.1074/JBC.M202107200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.87 Å)
Structure validation

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