Summary for 2VGB
| Entry DOI | 10.2210/pdb2vgb/pdb |
| Related | 1LIU 1LIW 1LIX 1LIY |
| Descriptor | PYRUVATE KINASE ISOZYMES R/L, 1,6-di-O-phosphono-beta-D-fructofuranose, 2-PHOSPHOGLYCOLIC ACID, ... (6 entities in total) |
| Functional Keywords | metal-binding, phosphorylation, pyruvate kinase in the active r-state, kinase, pyruvate, magnesium, glycolysis, transferase, disease mutation |
| Biological source | HOMO SAPIENS (HUMAN) |
| Total number of polymer chains | 4 |
| Total formula weight | 230258.03 |
| Authors | Valentini, G.,Chiarelli, L.,Fortin, R.,Dolzan, M.,Galizzi, A.,Abraham, D.J.,Wang, C.,Bianchi, P.,Zanella, A.,Mattevi, A. (deposition date: 2007-11-12, release date: 2007-11-20, Last modification date: 2023-12-13) |
| Primary citation | Valentini, G.,Chiarelli, L.R.,Fortin, R.,Dolzan, M.,Galizzi, A.,Abraham, D.J.,Wang, C.,Bianchi, P.,Zanella, A.,Mattevi, A. Structure and Function of Human Erythrocyte Pyruvate Kinase. Molecular Basis of Nonspherocytic Hemolytic Anemia. J.Biol.Chem., 277:23807-, 2002 Cited by PubMed: 11960989DOI: 10.1074/JBC.M202107200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.73 Å) |
Structure validation
Download full validation report
