2VDY

Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol

Summary for 2VDY

• Entry DOI: 10.2210/pdb2vdy/pdb
• Related: 2VDX
• Descriptor: CORTICOSTEROID-BINDING GLOBULIN, (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione (3 entities in total)
• Functional Keywords: glycoprotein, lipid-binding, steroid-binding, disease mutation, corticosteroid binding globulin, transport protein, cbg, serpin, cleaved, secreted, cortisol, transport
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted: P08185
• Total number of polymer chains: 2
• Total formula weight: 84096.10

Authors

Zhou, A.,Wei, Z.,Read, R.J. (deposition date: 2007-10-13, release date: 2008-05-13, Last modification date: 2023-12-13)

• Primary citation: Zhou, A.,Wei, Z.,Stanley, P.L.,Read, R.J.,Stein, P.E.,Carrell, R.W.; The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release.; J.Mol.Biol., 380:244-, 2008; PubMed: 18513745; DOI: 10.1016/J.JMB.2008.05.012

Experimental method

X-RAY DIFFRACTION (2.3 Å)