2V96

Structure of the unphotolysed complex of TcAChE with 1-(2- nitrophenyl)-2,2,2-trifluoroethyl-arsenocholine at 100K

Summary for 2V96

• Entry DOI: 10.2210/pdb2v96/pdb
• Related: 1ACJ 1ACL 1AMN 1AX9 1CFJ 1DX6 1E3Q 1E66 1EA5 1EEA 1EVE 1FSS 1GPK 1GPN 1GQR 1GQS 1H22 1H23 1HBJ 1JGA 1JGB 1JJB 1OCE 1ODC 1QID 1QIE 1QIF 1QIG 1QIH 1QII 1QIJ 1QIK 1QIM 1QTI 1SOM 1U65 1UT6 1VOT 1VXO 1VXR 1W4L 1W6R 1W75 1W76 1ZGB 1ZGC 2ACE 2ACK 2C4H 2C58 2C5F 2C5G 2CEK 2CKM 2CMF 2DFP 2J3D 2J3Q 2J4F 2V97 2V98 3ACE 4ACE
• Descriptor: ACETYLCHOLINESTERASE, 1-(2-nitrophenyl)-2,2,2-trifluoroethyl]-arsenocholine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: serine esterase, alternative splicing, acetylcholinesterase caged compounds kinetic crystallography partial q-weighted difference refinement backdoor, neurotransmitter degradation, lipoprotein, glycoprotein, cell junction, synapse, membrane, hydrolase, gpi-anchor
• Biological source: TORPEDO CALIFORNICA (PACIFIC ELECTRIC RAY)
• Total number of polymer chains: 2
• Total formula weight: 123834.71

Authors

Colletier, J.-P.,Sanson, B.,Royant, A.,Specht, A.,Nachon, F.,Masson, P.,Zaccai, G.,Sussman, J.L.,Goeldner, M.,Silman, I.,Bourgeois, D.,Weik, M. (deposition date: 2007-08-22, release date: 2007-11-20, Last modification date: 2023-12-13)

• Primary citation: Colletier, J.-P.,Royant, A.,Specht, A.,Sanson, B.,Nachon, F.,Masson, P.,Zaccai, G.,Sussman, J.L.,Goeldner, M.,Silman, I.,Bourgeois, D.,Weik, M.; Use of a 'Caged' Analog to Study Traffic of Choline within Acetylcholinesterase by Kinetic Crystallography; Acta Crystallogr.,Sect.D, 63:1115-, 2007; PubMed: 18007027; DOI: 10.1107/S0907444907044472

Experimental method

X-RAY DIFFRACTION (2.4 Å)