2V76

Crystal structure of the human dok1 PTB domain

Summary for 2V76

Entry DOI	10.2210/pdb2v76/pdb
Descriptor	DOCKING PROTEIN 1, TRIETHYLENE GLYCOL, SULFATE ION, ... (6 entities in total)
Functional Keywords	protein-binding, ptb domain, phosphorylation, adaptor protein, protein binding
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Isoform 1: Cytoplasm. Isoform 3: Cytoplasm, perinuclear region: Q53TY2
Total number of polymer chains	4
Total formula weight	49197.60
Authors	Oxley, C.L.,Anthis, N.J.,Lowe, E.D.,Campbell, I.D.,Wegener, K.L. (deposition date: 2007-07-26, release date: 2008-01-08, Last modification date: 2023-12-13)
Primary citation	Oxley, C.L.,Anthis, N.J.,Lowe, E.D.,Vakonakis, I.,Campbell, I.D.,Wegener, K.L. An Integrin Phosphorylation Switch: The Effect of {Beta}3 Integrin Tail Phosphorylation on Dok1 and Talin Binding. J.Biol.Chem., 283:5420-, 2008 Cited by PubMed: 18156175 DOI: 10.1074/JBC.M709435200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation