2V62

Structure of vaccinia-related kinase 2

Summary for 2V62

Entry DOI	10.2210/pdb2v62/pdb
Descriptor	SERINE/THREONINE-PROTEIN KINASE VRK2, MAGNESIUM ION, SUCCINIC ACID, ... (5 entities in total)
Functional Keywords	transferase, atp-binding, membrane, nucleotide-binding, transmembrane
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Isoform 1: Cytoplasm. Isoform 2: Cytoplasm: Q86Y07
Total number of polymer chains	2
Total formula weight	78848.38
Authors	Bunkoczi, G.,Eswaran, J.,Cooper, C.,Fedorov, O.,Keates, T.,Rellos, P.,Salah, E.,Savitsky, P.,Ugochukwu, E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.,Sundstrom, M.,Weigelt, J.,Knapp, S. (deposition date: 2007-07-13, release date: 2007-08-21, Last modification date: 2023-12-13)
Primary citation	Scheeff, E.D.,Eswaran, J.,Bunkoczi, G.,Knapp, S.,Manning, G. Structure of the Pseudokinase Vrk3 Reveals a Degraded Catalytic Site, a Highly Conserved Kinase Fold, and a Putative Regulatory Binding Site. Structure, 17:128-, 2009 Cited by PubMed: 19141289 DOI: 10.1016/J.STR.2008.10.018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation