2TUN

CONFORMATIONAL CHANGES IN THE (ALA-84-VAL) MUTANT OF TUMOR NECROSIS FACTOR

Summary for 2TUN

• Entry DOI: 10.2210/pdb2tun/pdb
• Descriptor: TUMOR NECROSIS FACTOR-ALPHA (1 entity in total)
• Functional Keywords: lymphokine
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Single-pass type II membrane protein. Tumor necrosis factor, membrane form: Membrane; Single-pass type II membrane protein. Tumor necrosis factor, soluble form: Secreted. C-domain 1: Secreted. C-domain 2: Secreted: P01375
• Total number of polymer chains: 6
• Total formula weight: 104380.69

Authors

Saludjian, P.,Prange, T. (deposition date: 1993-10-06, release date: 1994-01-31, Last modification date: 2013-06-19)

• Primary citation: Saludjian, P.,Prange, T.,Kahn, R.,Fourme, R.,Tavernier, J.,Van-Oostade, X.,Fiers, W.,Navaza, G.; Conformational Changes in the (Ala-84-Val) Mutant of Tumor Necrosis Factor; To be Published,

Experimental method

X-RAY DIFFRACTION (3.1 Å)