2TGD

LACK OF THE TRANSITION STATE STABILIZATION SITE IS A FACTOR IN THE INACTIVITY OF TRYPSINOGEN, A SERINE PROTEASE ZYMOGEN. STRUCTURE OF DFP INHIBITED BOVINE TRYPSINOGEN AT 2.1 ANGSTROMS RESOLUTION

2TGD の概要

• エントリーDOI: 10.2210/pdb2tgd/pdb
• 分子名称: TRYPSINOGEN, CALCIUM ION, DIISOPROPYL PHOSPHONATE, ... (4 entities in total)
• 機能のキーワード: hydrolase zymogen (serine proteinase)
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Secreted, extracellular space: P00760
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24219.19

構造登録者

Jones, M.O.,Stroud, R.M. (登録日: 1986-03-17, 公開日: 1986-05-07, 最終更新日: 2017-11-29)

• 主引用文献: Jones, M.O.,Stroud, R.M.; Lack of the Transition State Stabilization Site is a Factor in the Inactivity of Trypsinogen, a Serine Protease Zymogen. Structure of Dfp Inhibited Bovine Trypsinogen at 2.1 Angstroms Resolution; To be Published,

実験手法

X-RAY DIFFRACTION (2.1 Å)