2RQ8

Solution NMR structure of titin I27 domain mutant

Summary for 2RQ8

• Entry DOI: 10.2210/pdb2rq8/pdb
• Related: 1TIT
• Descriptor: Titin (1 entity in total)
• Functional Keywords: beta-sandwich, immunoglobulin-like domain, alternative splicing, atp-binding, calcium, calmodulin-binding, cardiomyopathy, coiled coil, cytoplasm, disease mutation, disulfide bond, immunoglobulin domain, isopeptide bond, kelch repeat, kinase, limb-girdle muscular dystrophy, magnesium, metal-binding, nucleotide-binding, nucleus, phosphoprotein, polymorphism, serine/threonine-protein kinase, tpr repeat, transferase, ubl conjugation, wd repeat
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm (Probable): Q8WZ42
• Total number of polymer chains: 1
• Total formula weight: 10930.48

Authors

Yagawa, K.,Oguro, T.,Momose, T.,Kawano, S.,Sato, T.,Endo, T. (deposition date: 2009-03-05, release date: 2010-02-02, Last modification date: 2021-11-10)

• Primary citation: Yagawa, K.,Yamano, K.,Oguro, T.,Maeda, M.,Sato, T.,Momose, T.,Kawano, S.,Endo, T.; Structural basis for unfolding pathway-dependent stability of proteins: Vectorial unfolding vs. global unfolding; Protein Sci., 2010; PubMed: 20095049; DOI: 10.1002/pro.346

Experimental method

SOLUTION NMR