2RMV

Solution structure of synthetic 26-mer peptide containing 142-166 sheep prion protein segment and C-terminal cysteine with Y155A mutation

2RMV の概要

• エントリーDOI: 10.2210/pdb2rmv/pdb
• 関連するPDBエントリー: 2RMW
• 分子名称: Major prion protein (1 entity in total)
• 機能のキーワード: tyrosine 155, synthetic prion peptide, disease mutation, glycoprotein, gpi-anchor, lipoprotein, membrane, polymorphism, protein fibril
• 細胞内の位置: Cell membrane; Lipid-anchor, GPI-anchor: P23907
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 3339.63

構造登録者

Bertho, G.,Bouvier, G.,Hui Bon Hoa, G.,Girault, J.-P. (登録日: 2007-11-28, 公開日: 2007-12-18, 最終更新日: 2021-11-10)

• 主引用文献: Bertho, G.,Bouvier, G.,Hui Bon Hoa, G.,Girault, J.-P.; Key role of the residue 155 in the mechanism of prion transconformation highlighted by the study of sheep mutant peptides; To be Published,

実験手法

SOLUTION NMR