2RHQ

PheRS from Staphylococcus haemolyticus- rational protein engineering and inhibitor studies

Summary for 2RHQ

• Entry DOI: 10.2210/pdb2rhq/pdb
• Related: 2RHS
• Descriptor: Phenylalanyl-tRNA synthetase alpha chain, Phenylalanyl-tRNA synthetase beta chain, ZINC ION, ... (5 entities in total)
• Functional Keywords: heterotetramer, phenylalanine, trna, aminoacyl-trna synthetase, atp-binding, cytoplasm, ligase, magnesium, metal-binding, nucleotide-binding, protein biosynthesis, rna-binding, trna-binding
• Biological source: Staphylococcus haemolyticus; More
• Cellular location: Cytoplasm : Q4L5E3 Q4L5E4
• Total number of polymer chains: 2
• Total formula weight: 122112.92

Authors

Evdokimov, A.G.,Mekel, M. (deposition date: 2007-10-09, release date: 2007-11-06, Last modification date: 2024-02-21)

• Primary citation: Evdokimov, A.G.,Mekel, M.,Hutchings, K.,Narasimhan, L.,Holler, T.,McGrath, T.,Beattie, B.,Fauman, E.,Yan, C.,Heaslet, H.,Walter, R.,Finzel, B.,Ohren, J.,McConnell, P.,Braden, T.,Sun, F.,Spessard, C.,Banotai, C.,Al-Kassim, L.,Ma, W.,Wengender, P.,Kole, D.,Garceau, N.,Toogood, P.,Liu, J.; Rational protein engineering in action: the first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus.; J.Struct.Biol., 162:152-169, 2008; PubMed: 18086534; DOI: 10.1016/j.jsb.2007.11.002

Experimental method

X-RAY DIFFRACTION (2.2 Å)