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2RA3

Human cationic trypsin complexed with bovine pancreatic trypsin inhibitor (BPTI)

Summary for 2RA3
Entry DOI10.2210/pdb2ra3/pdb
Related2R9P
DescriptorTrypsin-1, Pancreatic trypsin inhibitor, CALCIUM ION, ... (5 entities in total)
Functional Keywordshuman cationic trypsin, serine protease, bovine pancreatic trypsin inhibitor, bpti, calcium, digestion, disease mutation, hydrolase, metal-binding, secreted, sulfation, zymogen, pharmaceutical, protease inhibitor, serine protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P07477
Secreted: P00974
Total number of polymer chains4
Total formula weight63645.11
Authors
Salameh, M.A.,Soares, A.S.,Radisky, E.S. (deposition date: 2007-09-14, release date: 2007-12-11, Last modification date: 2023-08-30)
Primary citationSalameh, M.A.,Soares, A.S.,Hockla, A.,Radisky, E.S.
Structural Basis for Accelerated Cleavage of Bovine Pancreatic Trypsin Inhibitor (BPTI) by Human Mesotrypsin.
J.Biol.Chem., 283:4115-4123, 2008
Cited by
PubMed: 18077447
DOI: 10.1074/jbc.M708268200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.46 Å)
Structure validation

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