2R56

Crystal Structure of a Recombinant IgE Fab Fragment in Complex with Bovine Beta-Lactoglobulin Allergen

Summary for 2R56

Entry DOI	10.2210/pdb2r56/pdb
Descriptor	Beta-lactoglobulin, IgE Fab Fragment, light chain, IgE Fab Fragment, heavy chain, ... (4 entities in total)
Functional Keywords	allergen, ige, epitope, immunocomplex, lipocalin, fab, milk protein, polymorphism, retinol-binding, secreted, transport, immune system
Biological source	Bos taurus (cattle) More
Cellular location	Secreted: P02754
Total number of polymer chains	6
Total formula weight	130749.61
Authors	Niemi, M.,Kallio, J.M.,Hakulinen, N.,Rouvinen, J. (deposition date: 2007-09-03, release date: 2007-11-13, Last modification date: 2023-08-30)
Primary citation	Niemi, M.,Jylha, S.,Laukkanen, M.L.,Soderlund, H.,Makinen-Kiljunen, S.,Kallio, J.M.,Hakulinen, N.,Haahtela, T.,Takkinen, K.,Rouvinen, J. Molecular interactions between a recombinant IgE antibody and the beta-lactoglobulin allergen. Structure, 15:1413-1421, 2007 Cited by PubMed: 17997967 DOI: 10.1016/j.str.2007.09.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation