2R40

Crystal structure of 20E bound EcR/USP

Summary for 2R40

Entry DOI	10.2210/pdb2r40/pdb
Descriptor	Ecdysone Receptor, Ultraspiracle, CITRATE ANION, ... (8 entities in total)
Functional Keywords	nuclear receptor ligand-binding domain, anti-parallel alpha-helical sandwich, ecdysone receptor, ecr, gene regulation
Biological source	Heliothis virescens (tobacco budworm) More
Cellular location	Nucleus: O18473 Q7SIF6
Total number of polymer chains	2
Total formula weight	61888.54
Authors	Moras, D.,Billas, I.M.L.,Browning, C. (deposition date: 2007-08-30, release date: 2007-10-02, Last modification date: 2024-02-21)
Primary citation	Browning, C.,Martin, E.,Loch, C.,Wurtz, J.M.,Moras, D.,Stote, R.H.,Dejaegere, A.P.,Billas, I.M.L. Critical Role of Desolvation in the Binding of 20-Hydroxyecdysone to the Ecdysone Receptor J.Biol.Chem., 282:32924-32934, 2007 Cited by PubMed: 17848566 DOI: 10.1074/jbc.M705559200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.402 Å)

Structure validation