2QOG

Crotoxin B, the basic PLA2 from Crotalus durissus terrificus.

Summary for 2QOG

• Entry DOI: 10.2210/pdb2qog/pdb
• Related: 2OK9 2OQD
• Descriptor: Phospholipase A2 CB2, Phospholipase A2 CB1, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: crotoxin b cd-cdt basic-pla2, calcium, hydrolase, lipid degradation, metal-binding, secreted, neurotoxin, presynaptic neurotoxin
• Biological source: Crotalus durissus terrificus (tropical rattlesnake); More
• Cellular location: Secreted: P24027 P62022
• Total number of polymer chains: 4
• Total formula weight: 57083.85

Authors

Marchi-Salvador, D.P.,Correa, L.C.,Fontes, M.R.M. (deposition date: 2007-07-20, release date: 2008-04-01, Last modification date: 2011-07-13)

• Primary citation: Marchi-Salvador, D.P.,Correa, L.C.,Magro, A.J.,Oliveira, C.Z.,Soares, A.M.,Fontes, M.R.; Insights into the role of oligomeric state on the biological activities of crotoxin: crystal structure of a tetrameric phospholipase A2 formed by two isoforms of crotoxin B from Crotalus durissus terrificus venom.; Proteins, 72:883-891, 2008; PubMed: 18275084; DOI: 10.1002/prot.21980

Experimental method

X-RAY DIFFRACTION (2.28 Å)