2QM4

Crystal structure of human XLF/Cernunnos, a non-homologous end-joining factor

Summary for 2QM4

Entry DOI	10.2210/pdb2qm4/pdb
Related	1fu1 1ik9
Descriptor	Non-homologous end-joining factor 1 (2 entities in total)
Functional Keywords	xrcc4 like factor, homodimer, beta-sandwich, coiled-coil, recombination
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q9H9Q4
Total number of polymer chains	4
Total formula weight	108239.16
Authors	Li, Y.,Chirgadze, D.Y.,Sibanda, B.L.,Bolanos-Garcia, V.M.,Davies, O.R.,Blundell, T.L. (deposition date: 2007-07-14, release date: 2007-12-11, Last modification date: 2017-10-18)
Primary citation	Li, Y.,Chirgadze, D.Y.,Bolanos-Garcia, V.M.,Sibanda, B.L.,Davies, O.R.,Ahnesorg, P.,Jackson, S.P.,Blundell, T.L. Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ. Embo J., 27:290-300, 2008 Cited by PubMed: 18046455 DOI: 10.1038/sj.emboj.7601942 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation