2QL5

Crystal Structure of caspase-7 with inhibitor AC-DMQD-CHO

Summary for 2QL5

• Entry DOI: 10.2210/pdb2ql5/pdb
• Related: 2QL7 2QL9 2QLB 2QLF 2QLJ
• Related PRD ID: PRD_000431
• Descriptor: Caspase-7, inhibitor, peptide, ... (6 entities in total)
• Functional Keywords: cysteine protease, apoptosis, thiol protease, zymogen, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P55210 P55210
• Total number of polymer chains: 7
• Total formula weight: 63593.69

Authors

Agniswamy, J.,Fang, B.,Weber, I. (deposition date: 2007-07-12, release date: 2007-08-28, Last modification date: 2023-11-15)

• Primary citation: Agniswamy, J.,Fang, B.,Weber, I.T.; Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis.; Febs J., 274:4752-4765, 2007; PubMed: 17697120; DOI: 10.1111/j.1742-4658.2007.05994.x

Experimental method

X-RAY DIFFRACTION (2.34 Å)