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2QKI

Human C3c in complex with the inhibitor compstatin

Summary for 2QKI
Entry DOI10.2210/pdb2qki/pdb
Related1A1P 2A73 2A74 2I07 2ICE 2ICF
DescriptorComplement C3, compstatin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywordsimmunity, complement inhibitor design, c3, compstatin, immune system-hydrolase inhibitor complex, immune system/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P01024 P01024 P01024
Total number of polymer chains8
Total formula weight273113.36
Authors
Janssen, B.J.C.,Halff, E.F.,Lambris, J.D.,Gros, P. (deposition date: 2007-07-11, release date: 2007-08-14, Last modification date: 2023-08-30)
Primary citationJanssen, B.J.,Halff, E.F.,Lambris, J.D.,Gros, P.
Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition.
J.Biol.Chem., 282:29241-29247, 2007
Cited by
PubMed: 17684013
DOI: 10.1074/jbc.M704587200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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