2QEI

Crystal structure analysis of LeuT complexed with L-alanine, sodium, and clomipramine

Summary for 2QEI

Entry DOI	10.2210/pdb2qei/pdb
Related	2A65 2Q6H 2Q72 2QB4
Descriptor	Transporter, octyl beta-D-glucopyranoside, SODIUM ION, ... (6 entities in total)
Functional Keywords	membrane protein, neurotransmitter sodium symporter, occluded, tricyclic antidepressant, inhibitor, transmembrane, transport, transport protein
Biological source	Aquifex aeolicus
Total number of polymer chains	1
Total formula weight	60304.06
Authors	Singh, S.K.,Yamashita, A.,Gouaux, E. (deposition date: 2007-06-25, release date: 2007-08-21, Last modification date: 2023-08-30)
Primary citation	Singh, S.K.,Yamashita, A.,Gouaux, E. Antidepressant binding site in a bacterial homologue of neurotransmitter transporters. Nature, 448:952-956, 2007 Cited by PubMed: 17687333 DOI: 10.1038/nature06038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation