2QDT

Structural Basis for the Broad-Spectrum Inhibition of Metallo-{Beta}-Lactamases: L1- IS38 Complex

Summary for 2QDT

• Entry DOI: 10.2210/pdb2qdt/pdb
• Related: 2FM6 2FU9 2GKL
• Descriptor: Metallo-beta-lactamase L1, ZINC ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: hydrolase, zn, metallo, lactamase, inhibitor, l1
• Biological source: Stenotrophomonas maltophilia
• Cellular location: Periplasm (Potential): P52700
• Total number of polymer chains: 1
• Total formula weight: 29402.09

Authors

Garau, G.,Dideberg, O. (deposition date: 2007-06-21, release date: 2007-08-28, Last modification date: 2023-08-30)

• Primary citation: Lienard, B.M.,Garau, G.,Horsfall, L.,Karsisiotis, A.I.,Damblon, C.,Lassaux, P.,Papamicael, C.,Roberts, G.C.,Galleni, M.,Dideberg, O.,Frere, J.M.,Schofield, C.J.; Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols.; Org.Biomol.Chem., 6:2282-2294, 2008; PubMed: 18563261; DOI: 10.1039/b802311e

Experimental method

X-RAY DIFFRACTION (2 Å)